IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression

Neuroblastoma is the most common solid tumor in infants accounting for approximately 15% of all cancer-related deaths. Over 50% of high-risk neuroblastoma relapse, emphasizing the need of novel drug targets an...

Source: Molecular Cancer - May 29, 2023 Category: Cancer & Oncology Authors: Sven Hagemann, Danny Misiak, Jessica L. Bell, Tommy Fuchs, Marcell I. Lederer, Nadine Bley, Monika H ämmerle, Ehab Ghazy, Wolfgang Sippl, Johannes H. Schulte and Stefan Hüttelmaier Tags: Research Source Type: research