Dynamics of SARS-CoV-2 seroassay sensitivity: a systematic review and modelling study

ConclusionsSeroassay sensitivity decay depends on assay characteristics, and for some types of assays, it can make manufacturer specifications highly unreliable. We provide a tool to correct for this phenomenon and to assess the risk of decay for a given assay. Our analysis can guide the design and interpretation of serosurveys for SARS-CoV-2 and other pathogens and quantify systematic biases in the existing serology literature.

Source: Eurosurveillance - May 25, 2023 Category: Infectious Diseases Authors: Nana Owusu-Boaitey, Timothy W Russell, Gideon Meyerowitz-Katz, Andrew T Levin and Daniel Herrera-Esposito Source Type: research