TACE responser NDRG1 acts as a guardian against ferroptosis to drive tumorgenesis and metastasis in HCC

CONCLUSION: The constructed TACE response-related molecular subtypes and TRscores can specifically and accurately predict TACE prognosis for HCC. In addition, the TACE response-related hub gene NDRG1 may act as a guardian against ferroptosis to drive tumorgenesis and metastasis in HCC, which laid a new foundation for the development of new potential targeted therapy strategies to improve disease prognosis in HCC patients.PMID:37208604 | DOI:10.1186/s12575-023-00199-x

Source: Biological Procedures Online - May 19, 2023 Category: Molecular Biology Authors: Bufu Tang Yajie Wang Jinyu Zhu Jingjing Song Shiji Fang Qiaoyou Weng Yang Yang Jianfei Tu Zhongwei Zhao Minjiang Chen Min Xu Weiqian Chen Jiansong Ji Source Type: research