Role of the MyD88 Dependent Pathway in Degenerative Disc Disease

CONCLUSION: The most intense inflammatory process was observed in Modic type 1 degeneration, and the MyD88-dependent pathway was found to play a key role. While the most intense molecular increase was detected in Modic type 1 degeneration, the lowest levels were observed in Modic type III degeneration. It has been observed that the use of nonsteroidal anti-inflammatory drugs affects the inflammatory process through the MyD88 molecule.PMID:37144651 | DOI:10.5137/1019-5149.JTN.42017-22.2

Source: Turkish Neurosurgery - May 5, 2023 Category: Neurosurgery Authors: Mehmet Yigit Akgun Sibel Akyol Fatma Ozlen Orkhan Alizada Semih Can Cetintas Okan Turk Murat Hanci Source Type: research