< em > Angelica sinensis < /em > polysaccharides alleviate the oxidative burden on hematopoietic cells by restoring 5-fluorouracil-induced oxidative damage in perivascular mesenchymal progenitor cells

CONCLUSIONS: ASP delayed oxidative stress-induced premature senescence of 5-FU-treated feeder co-cultured hematopoietic cells via down-regulation of overactivated Wnt/β-catenin signaling. These findings provide a new strategy for alleviating myelosuppressive stress.PMID:37148130 | DOI:10.1080/13880209.2023.2207592
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Authors: Source Type: research