Current diagnostic and treatment strategies for urachal cancer

Orv Hetil. 2023 Apr 23;164(16):602-609. doi: 10.1556/650.2023.32754. Print 2023 Apr 23.ABSTRACTUrachal carcinoma is a rare malignancy that is uniquely associated with the field of urology. Urachal carcinoma is mostly diagnosed in urological care centers due to its most frequently presenting symptom that is hematuria. Currently available diagnostic and therapeutic knowledge is solely based on case reports and single center series, while no prospective clinical studies are carried out due to the modest number of patients. These circumstances have made creating professional guidelines challenging, hence the treatment of urachal carcinoma is commonly based on individual clinical decisions. In this review, we summarize the epidemiology, diagnostic modalities, prognosis as well as local and systemic therapeutic approaches of urachal carcinoma. Furthermore, we aim to draw conclusions from this knowledge base that may guide clinical decision-making. Finally, we highlight some of the novel therapeutic strategies that hold the potential to improve urachal carcinoma patients' prognosis and quality of life. Orv Hetil. 2023; 164(16): 602-609.PMID:37087728 | DOI:10.1556/650.2023.32754

Source: Orvosi Hetilap - April 23, 2023 Category: General Medicine Authors: Orsolya M ódos Melinda V áradi B álint Dér Attila Keszthelyi Mikl ós Szűcs Henning Reis P éter Nyirády Tibor Szarvas Source Type: research