Carriers of the p.P522R variant in PLC γ2 have a slightly more responsive immune system

The rs72824905 single-nucleotide polymorphism in the PLCG2 gene, encoding the p.P522R residue change in Phospholipase C gamma 2 (PLC γ2), associates with protection against several dementia subtypes and with incre...

Source: Molecular Neurodegeneration - April 20, 2023 Category: Neurology Authors: Annieck M. Diks, Cristina Teodosio, Bas de Mooij, Rick J. Groenland, Brigitta A. E. Naber, Inge F. de Laat, Sandra A. Vloemans, Susan Rohde, Marien I. de Jonge, Linda Lorenz, Debbie Horsten, Jacques J. M. van Dongen, Magdalena A. Berkowska and Henne Holst Tags: Research article Source Type: research