Variant in the dopamine-4-receptor gene (DRD4) in patients with type 1 diabetes

Conclusion Our data imply that the dopaminergic signaling pathways may play an important role in the etiology of DM1 as well as its comorbidities and will provide a new insight into the DM1 risk management. The -521C>T DRD4 gene polymorphism could be considered a genetic marker to predict susceptibility to DM1 as well as retinopathy and dyslipidemia progress in patients with already established disease.
Source: Neuroendocrinology - Category: Endocrinology Source Type: research