Best Practices for Physiologic Assessment of Coronary Stenosis

AbstractPurpose of ReviewThe goal of this review is to offer an updated and comprehensive summary of the available options for performing both invasive and noninvasive functional assessments of coronary artery disease.Recent FindingsFractional flow reserve (FFR) is an invasive functional coronary assessment of ischemia associated with clinical outcomes. In recent years, alternative pressure wire measurements that do not require hyperemic agents have been developed. Measurements such as instantaneous wave-free ratio (iFR) are non-inferior to FFR, result in shorter procedure times, and eliminate side effects related to the use of vasodilatory agents. With advances in technology and computational fluid dynamics, non-invasive methods based on invasive and non-invasive coronary angiograms have been developed to allow for hyperemia-free and wire-free assessments.SummaryAccurate methods to diagnose clinically significant ischemic heart disease are essential, and these novel systems are safer than they have been in the past. This review offers a comprehensive overview and guidance on best practices in conducting these assessments.
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research