Primary angiomatoid fibrous histiocytoma of the mandible with EWSR1-ATF1 fusion in an adult patient: case report and review of literature
Angiomatoid fibrous histiocytoma (AFH) is a rare intermediate malignant tumor that typically occurs in the soft tissues of the extremities in children and young adults. AFH arising in bone is very uncommon, and only seven cases have been reported in the literature. The wide morphologic spectrum and lack of a specific immunophenotype make the diagnosis of AFH challenging when it occurs in uncommon sites. Herein, we present a case of a 42-year-old male who was examined for right mandible pain, and cone beam computerized tomography (CBCT) demonstrated an expansile, lytic lesion of the right mandible with the destruction of cortical bone and invasion into soft tissue.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Min Hu, Fang Guo, Shiwei Xiao, Geling Zhangyang, Mingwei Wang, Junqiu Yue, Na Fang Tags: Case Report Source Type: research
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