Developmental and/or Epileptic Encephalopathy with Spike-and-Wave Activation in Sleep in Saudi Arabia: Electroclinical, Etiologic, Genetic, and Outcome Multicenter Study

As per the International League Against Epilepsy (ILAE), the continuum of developmental and/or epileptic encephalopathy with spike-and-wave activation in sleep (D/EE-SWAS) is characterized by seizures, specific electroencephalogram (EEG) patterns with dominant slow-sleep activation of interictal discharges, and marked stagnation or regression of neuropsychological function. [1] The EEG pattern associated with D/EE-SWAS was first qualified as electrical status epilepticus during sleep and was studied by selecting patients with at least 85% spike and wave index (SWI) during non-rapid eye movement (REM) sleep.

Source: Seizure: European Journal of Epilepsy - April 13, 2023 Category: Neurology Authors: Hanin Alsini, Abdulaziz Alghamdi, Shatha Alshafi, Khalid Hundallah, Sameer Almehmadi, Daad Alsowat, Suad Al-Yamani, Hanin Almuzaini, Ali Alwadie, Ali Al-Otaibi, Lamyaa Jad, Asma Almadhi, Fahad Bashiri, Amal Kentab, Muddathir H Hamad, Duaa Baarmah, Mohamme Source Type: research