LncRNA PVT1 delays skin photoaging by sequestering miR-551b-3p to release AQP3 expression via ceRNA mechanism

In conclusion, PVT1-driven suppression of miR-551b-3p induces AQP3 expression to inactivate the ERK/p38 MAPK signaling pathway, thereby inhibiting HDF senescence and ultimately delaying the skin photoaging.

http://link.springer.com/10.1007/s10495-023-01834-4

Source: Apoptosis - March 31, 2023 Category: Molecular Biology Source Type: research