Clinical applicability of the Polygenic Risk Score for breast cancer risk prediction in familial cases

Conclusions
Our results support the application of the PRS313 in risk prediction for genetically uninformative BC families and families with a PV in moderate BC risk genes.

Source: Journal of Medical Genetics - March 20, 2023 Category: Genetics & Stem Cells Authors: Lakeman, I. M. M., Rodriguez-Girondo, M. D. M., Lee, A., Celosse, N., Braspenning, M. E., van Engelen, K., van de Beek, I., van der Hout, A. H., Gomez Garcia, E. B., Mensenkamp, A. R., Ausems, M. G. E. M., Hooning, M. J., Adank, M. A., Hollestelle, A., Sc Tags: Open access Cancer genetics Source Type: research