Preclinical development and evaluation of nanobody-based CD70-specific CAR T cells for the treatment of acute myeloid leukemia

ConclusionCD70 expression in AML blasts was not fully supportive of its role in AML targeted therapy as reported. The combinational use of Chidamide and Decitabine with nb70CAR-T could provide a  new potential for the treatment of AML.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research