Effect of scan-time shortening on the 11C-PHNO binding potential to dopamine D3 receptor in humans and test –retest reliability

ConclusionThe scan-time shortening causes bias and decreasing test –retest reliability of11C-PHNO BPND. However, in the whole-body PET system, 90-min scan duration was sufficient for estimating the11C-PHNO BPND in the D3R-rich striatum and SN with small bias and at the test –retest reliability comparable to those derived from 120-min scans using the brain-dedicated PET systems.

http://rd.springer.com/10.1007/s12149-022-01819-4

Source: Annals of Nuclear Medicine - January 19, 2023 Category: Nuclear Medicine Source Type: research