Variation in the expression of interstitial cell of cajal-like cell (CD117) across congenital pelvic-ureteric junction obstruction and its renal sonological and functional correlation: A prospective observational study

Conclusion: The expression of ICC-LC shows a uniformly decreasing trend across obstruction when the severity of obstruction is less. Resurgence in the number of ICC-LC below PUJ in subjects with severe obstruction hints at the emergence of a new pacemaker area below severely blocked PUJ akin to that seen in complete heart block patients and deserves early attention.
Source: Journal of Indian Association of Pediatric Surgeons - Category: Surgery Authors: Source Type: research