Multiple mutations of IFITM3 are associated with COVID-19 susceptibilityregulation function of IFITM3 in COVID-19

Individuals have different symptoms of COVID-19 infection, which is not only caused by environmental and socioeconomic factors. Many studies have pointed out that it is closely related to genetic factors. We read with interest the publication by Li et al.1 reporting the relationship between Interferon-induced transmembrane protein 3 gene (IFIM3) polymorphisms and susceptibility and severity of COVID-19. Through a genotype study of 1989 samples, they found that the rs12252 of IFIM3 polymorphism was associated with COVID-19 susceptibility and severity, while rs34481144 was not.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research