< b > < i > Aspergillus fumigatus < /i > < /b > -Specific T Cells in Patients with Chronic Rhinosinusitis

Conclusion: Our findings indicate that patients with CRSwNP harbor a higher proportion ofA. fumigatus-reactive CD4+ T cells in the nasal mucosa than patients with CRSsNP.A. fumigatus-reactive CD4+ T cells of CRSwNP patients secreted TH2 cytokines and IL-17. Our findings suggest a role forA. fumigatus in the pathogenesis of CRSwNP and provide a rationale for targeted therapies.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - Category: Allergy & Immunology Source Type: research