Analysis of the anemia characteristics in early pregnancy and outcomes of pregnant women with hemoglobin H disease

CONCLUSIONS: The genotype missing type of pregnant women with Hb H disease was mainly -α3.7/--SEA and the non-missing type was mainly αCSα/--SEA. Hb H disease can easily cause various degrees of anemia (mainly moderate anemia in this study). Moreover, it can increase the incidence rate of pregnancy complications such as BTDP, oligohydramnios, FGR, and fetal distress, which will reduce the weight of neonates and seriously affect maternal and infant safety. Therefore, maternal anemia and fetal growth and development should be monitored during pregnancy and delivery, and transfusion therapy should be used to improve adverse pregnancy outcomes caused by anemia when necessary.PMID:36808349 | DOI:10.26355/eurrev_202302_31198

Source: European Review for Medical and Pharmacological Sciences - February 22, 2023 Category: Drugs & Pharmacology Authors: J-Y Su Y Chen H-F Chen J-R Tong Y-N Wei L-L Huang L Deng Source Type: research