Extracorporeal photopheresis in conditions of autoimmunity

Autoimmune disorders (AID) are chronic conditions that involve the loss of immunological tolerance to self-antigens, and result in systemic or tissue-specific damage. Current treatment regimens for AID are often nonspecific and involve long-term administration of immunosuppressive agents such as corticosteroids, calcineurin inhibitors, and cytotoxic chemotherapeutics[1]. While effective, these medications render the patient vulnerable to opportunistic infections, as well as increasing long-term risk of secondary malignancy[2].

Source: Transfusion and Apheresis Science - February 24, 2023 Category: Hematology Authors: Christopher Webb Tags: Review Source Type: research