Testicular architecture of men with 46,XX testicular Disorders of Sex Development

Conclusion: Testicular architecture and marker expression of SCs and LCs in 46,XX TDSD men display unique pattern, which are discernable from chromosomal aneuploidies. Given the reduced Y chromosomal gene content in 46,XX TDSD, the supernumerary X chromosome effects may be decisive regarding the damage on testicular composition and endocrine function.
Source: Sexual Development - Category: Biology Source Type: research