Improved Parkinsonian tremor quantification based on automatic label modification and SVM with RBF kernel

In this study, an automatic modification method for the labels judged by clinicians is pre sented to improve Parkinsonian tremor quantitation. Approach. For the severe overlapping of dynamic feature range between different severities, an outlier modification algorithm (PCA-IQR) based on the combination of principal component analysis and interquartile range statistic rule is proposed to l earn the blurred borders between different severity scores, thereby optimizing the labels. Afterward, according to the modified feature vectors, a support vector machine (SVM) with a radial basis function (RBF) kernel is proposed to classify the tremor severity. The classifier models of SVM with RBF kernel, k-nearest neighbors, and SVM with the linear kernel are compared. Main results. Experimental results show that the proposed method has high classification performance and excellent model generalization ability for tremor quantitation (accuracy: 97.93%, precision: 97.96%, sensitivity: 97.93% , F1-score: 97.94%). Significance. The proposed method may not only provide valuable assistance for clinicians to assess the tremor severity accurately, but also provides self-monitoring for patients at home and improve the assessment skills of clinicians.

Source: Physiological Measurement - February 20, 2023 Category: Physiology Authors: Yumin Li, Zengwei Wang and Houde Dai Source Type: research