Size matters: HDL particle populations and the risk of infection

Nature Reviews Cardiology, Published online: 15 February 2023; doi:10.1038/s41569-023-00844-8Low plasma levels of HDL cholesterol are a risk factor for infection and hospitalization for infectious disease. Recent work suggests that inadequate levels of HDL particles of specific sizes — small and medium — account for this risk. In this Comment, we discuss the mechanistic implications of these observations and the methodologies used to quantify HDL size.
Source: Nature Reviews Cardiology - Category: Cardiology Authors: Source Type: research