Regulatory T Cells are Necessary for Generation of CD8+ Tissue Resident Memory T cells Following Influenza Infection

Respiratory viral infections such as influenza are an important cause of morbidity and mortality. Understanding the immune mechanisms behind generation of protective memory responses is valuable in discovering potential therapies. The aim of our study was to determine whether regulatory T cells (Treg) promote the generation of CD8+ tissue resident memory T cells (Trm) following influenza infection in mice.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research