Williams Syndrome: Supravalvar Aortic, Aortic Arch, Coronary and Pulmonary Arteries: Is Comprehensive Repair Advisable and Achievable?

Williams syndrome, and various elastin protein mediated arteriopathies, presents a clinical challenge to pediatric cardiovascular specialists. In the severest phenotypes, multilevel obstruction to the systemic and pulmonic arterial systems result in biventricular dysfunction which can be imminently life-threatening. As a longstanding, quaternary referral center for complex pulmonary arteriopathies and pediatric connective tissue disease, Stanford Medicine Children's Health has developed a sizeable experience managing these patients.

Source: Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual - February 2, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Michael Ma, Elisabeth Martin, Claudia Algaze, Ronnie Thomas Collins, Doff McElhinney, Richard Mainwaring, Frank Hanley Source Type: research