Correlation of serum Adenosine Deaminase levels with microbiological parameters in Pulmonary Tuberculosis

This study aims to find the association of serum adenosine deaminase (a biomarker) with the various microbiological parameters like sputum smear microscopy, culture and CBNAAT in pulmonary tuberculosis patients. A total of 40 cases were collected from November 2019 to October 2021, and the presumptive cases of pulmonary tuberculosis diagnosed by Ziehl –Neelsen staining for acid fast bacilli and/or CBNAAT were recruited. Serum adenosine deaminase levels were estimated.The following variables were significantly associated (p <  0.05) with serum adenosine deaminase levels: age, sputum smear microscopy findings, time to culture positivity, CBNAAT category and Ct value (Mean).This study does witness few significant correlations between serum adenosine deaminase levels and various microbiological parameters used in diagnosi s of TB, which can be further explored and utilised in diagnosis and treatment of pulmonary tuberculosis.
Source: Indian Journal of Clinical Biochemistry - Category: Biochemistry Source Type: research