Biallelic CFAP61 variants cause male infertility in humans and mice with severe oligoasthenoteratozoospermia

Conclusions
Our findings indicate that CFAP61 is essential for spermatogenesis and that biallelic CFAP61 variants lead to male infertility in humans and mice with OAT.

Source: Journal of Medical Genetics - January 24, 2023 Category: Genetics & Stem Cells Authors: Hu, T., Meng, L., Tan, C., Luo, C., He, W.-B., Tu, C., Zhang, H., Du, J., Nie, H., Lu, G.-X., Lin, G., Tan, Y.-Q. Tags: Gametes Source Type: research