Cancers, Vol. 15, Pages 694: Survival of Testicular Pure Teratoma vs. Mixed Germ Cell Tumor Patients in Primary Tumor Specimens across All Stages

Cancers, Vol. 15, Pages 694: Survival of Testicular Pure Teratoma vs. Mixed Germ Cell Tumor Patients in Primary Tumor Specimens across All Stages Cancers doi: 10.3390/cancers15030694 Authors: Cristina Cano Garcia Francesco Barletta Reha-Baris Incesu Mattia Luca Piccinelli Stefano Tappero Andrea Panunzio Zhe Tian Fred Saad Shahrokh F. Shariat Alessandro Antonelli Carlo Terrone Ottavio De Cobelli Markus Graefen Derya Tilki Alberto Briganti Mike Wenzel Severine Banek Luis A. Kluth Felix K. H. Chun Pierre I. Karakiewicz We aimed to test for survival differences between testicular pure teratoma vs. mixed germ cell tumor (GCT) patients in a stage-specific fashion. Pure teratoma and mixed GCT in primary tumor specimens were identified within the Surveillance, Epidemiology, and End Results database (2004–2019). Kaplan–Meier curves depicted five-year overall survival (OS) and subsequently, cumulative incidence plots depicted cancer-specific mortality (CSM) and other-cause mortality (OCM) in a stage-specific fashion. Multivariable competing risks regression (CRR) models were used. Of 9049 patients, 299 (3%) had pure teratoma. In stage I, II and III, five-year OS rates differed between pure teratoma and mixed GCT (stage I: 91.6 vs. 97.2%, p < 0.001; stage II: 100 vs. 95.9%, p < 0.001; stage III: 66.8 vs. 77.8%, p = 0.021). In stage I, survival differences originated from higher OCM (6.4 vs. 1...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research