Clinical and Genetic Characteristics of BCG Disease in Chinese Children: a Retrospective Study

ConclusionGreater than 80% of BCG patients have PID; accordingly, gene sequencing should be performed in patients with BCG disease for early diagnosis. BCG disease behaves differently in patients with different types of PID. Patients without identified genetic etiology had similar outcomes to PID patients, which hints that they may have pathogenic gene mutations that need to be discovered.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research