What role for asbestos in idiopathic pulmonary fibrosis? Findings from the IPF job exposures case-control study

Conclusion
Occupational asbestos exposure alone, or through interaction with MUC5B rs35705950 genotype, was not associated with IPF. Exposure to asbestos and smoking interact to increase IPF risk in carriers of a common genetic variant, the minor allele of MUC5B rs35705950.

Trial registration number
NCT03211507.

Source: Occupational and Environmental Medicine - January 18, 2023 Category: Occupational Health Authors: Reynolds, C. J., Sisodia, R., Barber, C., Moffatt, M., Minelli, C., De Matteis, S., Cherrie, J. W., Newman Taylor, A., Cullinan, P. Tags: Open access Workplace Source Type: research