p85S6K sustains synaptic GluA1 to ameliorate cognitive deficits in Alzheimer ’s disease

ConclusionsThese results strongly imply a significant role for p85S6K in maintaining synaptic and cognitive function by interacting with GluA1. The findings provide an insight into the rational targeting of p85S6K as a therapeutic potential for AD.

http://link.springer.com/10.1186/s40035-022-00334-w

Source: Translational Neurodegeneration - January 9, 2023 Category: Neurology Source Type: research