Identification of two novel FUT1 mutations in people with Bombay phenotype from Iran

Bombay and Para-Bombay phenotypes are characterized by FUT1 gene mutation and lack of H antigen expression in red blood cells. ABH antigens are not present in the body secretions of Bombay individuals, while they are expressed in the secretions of para-Bombay. The aim of this study was to investigate the molecular basis of FUT1 and FUT2 genes in Iranians with the Bombay or Para-Bombay phenotype.
Source: Transfusion and Apheresis Science - Category: Hematology Authors: Source Type: research