Effect of intensive lifestyle intervention on the association between weight variability and major adverse cardiovascular events in overweight or obese adults with type 2 diabetes mellitus

ConclusionsAmong the overweight or obese individuals with type 2 diabetes mellitus, rising weight variability was independently associated with increased MACE risks in the DSE arm. Therefore, a guideline-recommended ILI strategy for weight loss should be adopted to improve cardiovascular outcomes without worrying about the effect of weight fluctuations.

Source: Journal of Diabetes Investigation - January 4, 2023 Category: Endocrinology Authors: Xiangbin Zhong, Xingfeng Xu, Menghui Liu, Peng Wang, Lixiang He, Odong Christopher, Shaozhao Zhang, Yifen Lin, Yiquan Huang, Zhenyu Xiong, Xiaodong Zhuang, Xinxue Liao Tags: Original Article Source Type: research