Celecoxib reduces hyperalgesia and tactile allodynia in diabetic rats.

CONCLUSIONS: Data suggest that celecoxib produces an antihyperalgesic and antiallodynic effect in diabetic rats. These effects seem to result from activation of μ, δ and κ opioid receptors for antinociception and μ and δ for antiallodynia. Celecoxib could be useful to treat neuropathic pain in diabetic patients. PMID: 25933968 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/25933968?dopt=Abstract

Source: Pharmacological Reports - May 4, 2015 Category: Drugs & Pharmacology Authors: Juárez-Rojop IE, Morales-Hernández PE, Tovilla-Zárate CA, Bermúdez-Ocaña DY, Torres-Lopez JE, Ble-Castillo JL, Díaz-Zagoya JC, Granados-Soto V Tags: Pharmacol Rep Source Type: research