Development of an efficient extraction methodology to analyse potential inflammatory biomarkers from sebum

Conclusion: The study revealed that there was a high degree of variability in the extraction efficiency of different cytokines. However, improved efficiency was achieved across all cyto kines with selective surfactants and mechanical stimuli. The optimised protocol will provide means to detect low levels of potential biomarkers from skin surface, enabling the evaluation of local changes in pro- and anti-inflammatory cytokines present in different skin conditions.
Source: Skin Pharmacology and Physiology - Category: Dermatology Source Type: research