Human iPSC-derived neural stem cells with ALDH5A1 mutation as a model of succinic semialdehyde dehydrogenase deficiency

Succinic semialdehyde dehydrogenase deficiency (SSADH-D) is an autosomal recessive gamma-aminobutyric acid (GABA) metabolism disorder that can arise due to ALDH5A1 mutations, resulting in severe, progressive, unt...

Source: BMC Neuroscience - December 16, 2022 Category: Neuroscience Authors: Xiaodan Chen, Minzhi Peng, Yanna Cai, Chengcheng Zhou and Li Liu Tags: Research Source Type: research