Upper airway microbiome transplantation for patients with chronic rhinosinusitis

ConclusionsNasal microbiome transplants obtained from healthy individuals and administered as nasal lavages to patients with CRSsNP are feasible. The patients reported significant and lasting reduction of symptoms and these findings were associated with a lasting increase in abundance and diversity of the local bacterial flora. The observations, which need to be confirmed by randomized controlled trials, may constitute a new treatment avenue for these difficult to treat patients where antibiotics only provides short lasting symptom control.Trial registration number: NCT03122795.This article is protected by copyright. All rights reserved

Source: International Forum of Allergy and Rhinology - December 14, 2022 Category: Allergy & Immunology Authors: Anders M årtensson, Charlotte Cervin‐Hoberg, Flavia Huygens, Malin Lindstedt, Christina Sakellariou, Lennart Greiff, Anders Cervin Tags: ORIGINAL ARTICLE Source Type: research