Sex ‐related differences in premature cardiovascular disease in familial hypercholesterolemia

Familial hypercholesterolemia (FH) is an inherited condition marked by elevated blood levels of low-density lipoprotein cholesterol (LDL-C) starting in utero due most often to a monogenic mutation in the LDL-receptor. Frequency is approximately 1 in 250 in the general population and higher in several founder groups. It is well established that individuals with FH have an elevated lifetime risk of atherosclerotic cardiovascular disease (ASCVD) and are also at an increased risk of premature ASCVD (defined as
Source: Journal of Clinical Lipidology - Category: Lipidology Authors: Tags: Original Research Source Type: research