Extracorporeal life support allows lung transplant in anti-MDA5+ rapidly progressive-interstitial lung disease.

Conclusions: The results provide crucial information for the management of anti-MDA5 RP-ILD. The bridge-to-recovery strategy in anti-MDA5 RP-ILD patients requiring ECLS despite specific prior treatment leads to undesirable results. In contrast, a bridge-to-emergency lung transplantation is not only feasible but also associated with a favorable outcome and appears therefore as the sole hope of survival.

Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Bay, P., Pineton De Chambrun, M., Roux, A., Bunel, V., Combes, A., Israël Biet, D., Zuber, B., Nunes, H., Allenbach, Y., Uzunhan, Y. Tags: 02.01 - Acute critical care Source Type: research