NLRP3 inflammasome deficiency attenuates cerebral ischemia-reperfusion injury by inhibiting ferroptosis

CONCLUSION: Inhibition of the NLRP3 inflammasome alleviates CIRI by inhibiting ferroptosis and inflammation, possibly through a mechanism of the Keap1-Nrf2 pathway.PMID:36435361 | DOI:10.1016/j.brainresbull.2022.11.016

Source: Cell Research - November 26, 2022 Category: Cytology Authors: Zhuo Wang Yina Li Yingze Ye Hua Zhu Jing Zhang Huijuan Wang Jiaxi Lei Lijuan Gu Liying Zhan Source Type: research