Aberrant DNA methylation and expression of EYA4 in gastric cardia intestinal metaplasia

Conclusions: Detection rates of gastric cardiac IM increase with age and are higher in men. Our findings highlight the important role of promoter hypermethylation and downregulation of EYA4 in gastric cardiac IM development.

Source: The Saudi Journal of Gastroenterology - November 24, 2022 Category: Gastroenterology Authors: Chenxi Li Zhaohui Liu Guohua Xu Shibin Wu Yunhui Peng Ruinuan Wu Shukun Zhao Xiaoqi Liao Runhua Lin Source Type: research