Expression analysis of aryl hydrocarbon receptor repressor (AHRR) gene in gallbladder cancer
Conclusion: In conclusion, the present study suggests that low AHRR expression may be critical in gallbladder cancer development. Our data suggests that AHRR may act as a tumor suppressor gene and its expression profile may be useful as a diagnostic marker in gallbladder cancer. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 24, 2021 Category: Gastroenterology Authors: Puneet Kumar Manoj Yadav Khushi Verma Ruhi Dixit Juhi Singh Satyendra K Tiwary Gopeshwar Narayan VK Dixit Source Type: research

Proposal for a clinicopathological prognostic score for resected gastric cancer patients
Conclusion: A prognostic model comprising histological features such as Laurén subtype can be easily applied in clinical practice, and provides more prognostic information than pTNM stage alone. These models can further stratify resected GC patients and have the potential to aid in the individualization of patient management. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 24, 2021 Category: Gastroenterology Authors: Cristina D í az del Arco Lourdes Estrada Mu & #241;oz Elena Molina Rold & #225;n Luis Ortega Medina Soledad Garc & #237;a G & #243;mez de las Heras & #193;ngela Ch & #225;vez Ma Jes & #250;s Fern & #225;ndez Ace & #241;ero Source Type: research

Clinical characteristics and efficacy of endoscopic treatment of gastrointestinal ectopic varices: A single-center study
Conclusion: Age, erythema, and the location of EcVs are considered risk factors for EcV bleeding, and the rate of bleeding is higher in patients with duodenal varices than in those with other EcVs. Endoscopic treatment is safe, effective, and feasible for controlling EcV bleeding. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 24, 2021 Category: Gastroenterology Authors: Wan Yipeng Wang Anjiang Li Bimin Huang Chenkai Wan Size Zhu Xuan Source Type: research

Time trends of causes of upper gastrointestinal bleeding and endoscopic findings
Conclusions: NVUGIB composed the majority of cases presenting with UGIB and variceal bleeding was lower than that described in prior studies, but there were no clear trends in the proportion of causes of UGIB during the study duration. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 24, 2021 Category: Gastroenterology Authors: Ibrahim M Alruzug Thamer A Aldarsouny Toufic Semaan Manhal K Aldaher Adnan AlMustafa Nahla Azzam Abdulrahman Aljebreen Majid A Almadi Source Type: research

Upper gastrointestinal bleeding: Causes and patient outcomes
Conclusion: Causes of UGIB in this patient population were predominantly nonvariceal and the rebleeding and mortality rates resembled those of other studies. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 24, 2021 Category: Gastroenterology Authors: Majid A Almadi Abdulelah Almutairdi Ibrahim M Alruzug Thamer A Aldarsouny Toufic Semaan Manhal K Aldaher Adnan AlMustafa Nahla Azzam Faisal Batwa Badr Albawardy Abdulrahman Aljebreen Source Type: research

Restrictive versus liberal transfusion strategy in upper gastrointestinal bleeding: A randomized controlled trial
Conclusion: Restrictive transfusion strategy is non-inferior to liberal transfusion strategy in patients with UGIB. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 24, 2021 Category: Gastroenterology Authors: Gautham Kola Sathasivam Sureshkumar Subair Mohsina GS Sreenath Vikram Kate Source Type: research

New insights into intestinal failure & #8211;associated liver disease in adults: A comprehensive review of the literature
Fotios S Fousekis, Ioannis V Mitselos, Dimitrios K ChristodoulouSaudi Journal of Gastroenterology 2021 27(1):3-12 Intestinal failure–associated liver disease (IFALD) remains one of the most common and serious complications of parenteral nutrition (PN), causing a wide spectrum of hepatic manifestations from steatosis and mild cholestasis to portal hypertension and end-stage liver failure. The prevalence of IFALD depends on the diagnostic criteria and ranges from 4.3% to 65%. Moreover, many factors are shown to contribute to its development, including nutrient deficiencies, toxicity of PN, infections, and alte...
Source: The Saudi Journal of Gastroenterology - February 24, 2021 Category: Gastroenterology Authors: Fotios S Fousekis Ioannis V Mitselos Dimitrios K Christodoulou Source Type: research

Improving outcomes in patients with acute upper gastrointestinal bleeding
James Y. W. LauSaudi Journal of Gastroenterology 2021 27(1):1-2 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - February 24, 2021 Category: Gastroenterology Authors: James Y. W. Lau Source Type: research

Evaluation of the safety and efficacy of minimal endoscopic sphincterotomy followed by papillary balloon dilation for the removal of common bile duct stones
Conclusions: ESBD is more efficient and safer in the management of CBD stones than EST. A prospective randomized study comparing ESBD with EST is needed to establish this combination technique. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 27, 2020 Category: Gastroenterology Authors: Shigeto Ishii Toshio Fujisawa Mako Ushio Sho Takahashi Wataru Yamagata Yusuke Takasaki Akinori Suzuki Yoshihiro Okawa Kazushige Ochiai Ko Tomishima Ryo Kanazawa Hiroaki Saito Shuichiro Shiina Hiroyuki Isayama Source Type: research

Post pancreaticoduodenectomy hemorrhage: A retrospective analysis of incidence, risk factors and outcome
Conclusion: PPH occurred in 11.5% of patients and resulted in a mortality four times greater than those without a PPH. It occurred more frequently in patents with a high pre-operative serum bilirubin, INR, biliary stenting or those with a PJ leak. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 27, 2020 Category: Gastroenterology Authors: Subhashish Das Samrat Ray Vivek Mangla Siddharth Mehrotra Shailendra Lalwani Naimish N Mehta Amitabh Yadav Samiran Nundy Source Type: research

Developing a risk prediction model for multidrug-resistant bacterial infection in patients with biliary tract infection
Conclusions: This simple bedside prediction tool to predict multidrug-resistant bacterial infection can help clinicians identify low versus high risk patients as well as choose appropriate, timely initial empirical antibiotics therapy. This model should be validated before it is widely applied in clinical settings. we can differentiate between (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 27, 2020 Category: Gastroenterology Authors: Yingying Hu Kongying Lin Kecan Lin Haitao Lin Ruijia Chen Shengcong Li Jinye Wang Yongyi Zeng Jingfeng Liu Source Type: research

Efficacy of single- versus split-dose polyethylene glycol electrolyte solution for morning colonoscopy: A randomized controlled study
Conclusion: For morning colonoscopy, split-dose 2 L PEG is superior to single-dose 2 L PEG by improved bowel preparation, better tolerability, and patient satisfaction. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 27, 2020 Category: Gastroenterology Authors: Jing Shan Mei Yang Wenbin Ran Weidong Xi Lin Jiang Xiaobin Sun Source Type: research

Clinical features of Epstein & #8211;Barr virus in the intestinal mucosa and blood of patients with inflammatory bowel disease
Conclusion: Elderly patients with IBD, treated with azathioprine, are more susceptible to EBV positivity. Further, EBV mucosal detection correlated with the severity of mucosal damage and refractoriness, but not prognosis. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 27, 2020 Category: Gastroenterology Authors: Jin-Qiu Zhou Li Zeng Qiao Zhang Xin-Yao Wu Meng-Lan Zhang Xing-Tao Jing Yu-Fang Wang Hua-Tian Gan Source Type: research

Successful response of intradermal hepatitis B vaccine in nonresponders of intramuscular hepatitis B vaccine in general and hemodialysis population
Conclusion: For those not responding to the conventional IM route of the hepatitis B vaccine, the ID route is an effective way of immunization in this group and this approach would lead to a decrease in infection rates in the vulnerable population such as those on hemodialysis. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 27, 2020 Category: Gastroenterology Authors: Farina M Hanif Nasir Mehmood Zain Majid Nasir H Luck S Mudassir Laeeq Abbas A Tasneem Muhammad Manzoor ul Haque Source Type: research

Nonclostridium difficile enteric infection and the risk of developing inflammatory bowel disease: A systematic review and meta-analysis
Conclusion: Our meta-analysis has found that patients with non-CDI enteric infection were associated with an increased risk of IBD. Future studies are needed to determine the association between non-CDI enteric infection and the risk of developing IBD and elucidate the potential underlying mechanisms. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 27, 2020 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Ming-Jun Sun Source Type: research

Nutrition and the gut microbiome during critical illness: A new insight of nutritional therapy
Sara ZaherSaudi Journal of Gastroenterology 2020 26(6):290-298 Changes in the microbiome in response to environmental influences can affect the overall health. Critical illness is considered one of the major environmental factors that can potentially influence the normal gut homeostasis. It is associated with pathophysiological effects causing damage to the intestinal microbiome. Alteration of intestinal microbial composition during critical illness may subsequently compromise the integrity of the intestinal epithelial barrier and intestinal mucosa absorptive function. Many factors can impact the microbiome of critically ...
Source: The Saudi Journal of Gastroenterology - November 27, 2020 Category: Gastroenterology Authors: Sara Zaher Source Type: research

Nonresponse to intramuscular vaccination: An unmet need in hepatitis B vaccination
Sara Manti, Giuseppe F Parisi, Salvatore LeonardiSaudi Journal of Gastroenterology 2020 26(6):287-289 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 27, 2020 Category: Gastroenterology Authors: Sara Manti Giuseppe F Parisi Salvatore Leonardi Source Type: research

Response to Almalki et al.: Resuming endoscopy services during the COVID-19 pandemic
Majid A Almadi, Abdulrahman M Aljebreen, Nahla Azzam, Faisal BatwaSaudi Journal of Gastroenterology 2020 26(5):285-286 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Majid A Almadi Abdulrahman M Aljebreen Nahla Azzam Faisal Batwa Source Type: research

A call for structured re-opening of endoscopy services during the COVID-19 pandemic
Ahmad S Almalki, Mohammed Khan, Turki AlAmeelSaudi Journal of Gastroenterology 2020 26(5):283-284 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Ahmad S Almalki Mohammed Khan Turki AlAmeel Source Type: research

Guidance and workflow of endoscopy reopening during COVID-19 pandemic
Nahla Azzam, Nora Alotaibi, Majid Almadi, Abdulrahman AljebreenSaudi Journal of Gastroenterology 2020 26(5):279-282 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Nahla Azzam Nora Alotaibi Majid Almadi Abdulrahman Aljebreen Source Type: research

Abnormal liver-related biomarkers in COVID-19 patients and the role of prealbumin
Conclusions: Abnormalities in albumin and prealbumin levels are common among COVID-19 patients and hypoprealbuminemia independently predicts adverse outcome and should be carefully considered in clinical practice. Moreover, changes in liver-related biomarkers is not a salient feature of COVID-19. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Tao Li Ying Guo Xianghua Zhuang Laigang Huang Xingqian Zhang Fengtao Wei Baohua Yang Source Type: research

A cross-sectional survey on the psychological impact of the COVID-19 pandemic on inflammatory bowel disease patients in Saudi Arabia
Conclusions: Many patients expressed symptoms of anxiety, although not depression. Female patients, patients educated till a high school diploma, and those with indeterminate colitis were more likely to have anxiety. IBD patients require greater attention during a pandemic to avoid adverse disease-related outcomes. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Mahmoud Mosli Mansour Alourfi Amani Alamoudi Almoutaz Hashim Omar Saadah Eman Al Sulais Turki AlAmeel Othman Alharbi Shakir Bakari Yaser Meeralam Seigha Alshobai Majid Alsahafi Hani Jawa Yousif Qari Source Type: research

Disability and quality of life before and during the COVID-19 outbreak: A cross-sectional study in inflammatory bowel disease patients
Conclusion: The current study showed that disability and HRQoL appears to be unaffected by the COVID-19 pandemic among our cohort, however further studies with longer follow up and larger sample size is needed. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Nahla A Azzam Abdulrahman Aljebreen Arwa Almuhareb Majid A Almadi Source Type: research

The psychological impact of COVID-19 pandemic on physicians in Saudi Arabia: A cross-sectional study
Conclusions: The COVID-19 pandemic had a negative psychological effect on physicians in Saudi Arabia. Gender, age, and previous exposure to similar traumatic events were predictive of psychological reactions to the pandemic in this population. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Eman Al Sulais Mahmoud Mosli Turki AlAmeel Source Type: research

COVID-19 and endoscopy services in intermediately affected countries: a position statement from the saudi gastroenterology association
Majid A Almadi, Abdulrahman M Aljebreen, Nahla Azzam, Nuha Alammar, Emad S Aljahdli, Fahad I Alsohaibani, Resheed Alkhiari, Abdulaziz O Almasoud, Mohammad S Al Beshir, Suliman Alshankiti, Ahmad W Alharbi, Mohammed Alkhathami, Faisal BatwaSaudi Journal of Gastroenterology 2020 26(5):240-248 With the global pandemic due to coronavirus disease 2019 (COVID-19), there has been a significant strain on healthcare facilities. The infectivity rate, as well as the rate of healthcare workers who have fallen ill to the disease, has raised concerns globally on the proper management of patients as well as the role of safe healthcare pr...
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Majid A Almadi Abdulrahman M Aljebreen Nahla Azzam Nuha Alammar Emad S Aljahdli Fahad I Alsohaibani Resheed Alkhiari Abdulaziz O Almasoud Mohammad S Al Beshir Suliman Alshankiti Ahmad W Alharbi Mohammed Alkhathami Faisal Batwa Source Type: research

Saudi association for the study of liver diseases and transplantation position statement on liver transplantation during the COVID-19 pandemic
Bandar Al-Judaibi, Reem Almaghrabi, Mohammed Alghamdi, Waleed K Al-Hamoudi, Mohammed AlQahtani, Faisal Abaalkhail, Mohammed Shagrani, Faisal M SanaiSaudi Journal of Gastroenterology 2020 26(5):233-239 The World Health Organization (WHO), on March 11th 2020, upgraded the status of the novel coronavirus disease (COVID-19) from epidemic to pandemic. Over two million individuals have been infected with SARS-CoV-2, the virus causing COVID-19, and as of April, 14th 2020, there were over 5000 confirmed cases in Saudi Arabia (SA). Many countries, including SA, have imposed major restrictions on travel, and everyday life, and the ...
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Bandar Al-Judaibi Reem Almaghrabi Mohammed Alghamdi Waleed K Al-Hamoudi Mohammed AlQahtani Faisal Abaalkhail Mohammed Shagrani Faisal M Sanai Source Type: research

Gastrointestinal and liver manifestations of COVID-19
Janice Cheong, Nichoals Bartell, Thoetchai Peeraphatdit, Mahmoud Mosli, Bandar Al-JudaibiSaudi Journal of Gastroenterology 2020 26(5):226-232 The novel coronavirus 2 (SARS-CoV-2) has spread worldwide. While patients typically present with fever and symptoms of a respiratory illness, patients have also presented with gastrointestinal symptoms such as diarrhea, vomiting and abdominal pain. In addition, some patients were reported to have liver injury. In this article, we review gastrointestinal and liver aspects of COVID-19. In addition, we provide general gastroenterologists with guidance on the management of patients with...
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Janice Cheong Nichoals Bartell Thoetchai Peeraphatdit Mahmoud Mosli Bandar Al-Judaibi Source Type: research

COVID-19 in gastroenterology and hepatology: Living with the realities of a historic 21st century pandemic
Eric M Yoshida, Trana Hussaini, Majid AlsahafiSaudi Journal of Gastroenterology 2020 26(5):223-225 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Eric M Yoshida Trana Hussaini Majid Alsahafi Source Type: research

Response to Almalki et al.: Resuming endoscopy services during the COVID-19 pandemic
Majid A Almadi, Abdulrahman M Aljebreen, Nahla Azzam, Faisal BatwaSaudi Journal of Gastroenterology 2020 26(5):285-286 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Majid A Almadi Abdulrahman M Aljebreen Nahla Azzam Faisal Batwa Source Type: research

A call for structured re-opening of endoscopy services during the COVID-19 pandemic
Ahmad S Almalki, Mohammed Khan, Turki AlAmeelSaudi Journal of Gastroenterology 2020 26(5):283-284 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Ahmad S Almalki Mohammed Khan Turki AlAmeel Source Type: research

Guidance and workflow of endoscopy reopening during COVID-19 pandemic
Nahla Azzam, Nora Alotaibi, Majid Almadi, Abdulrahman AljebreenSaudi Journal of Gastroenterology 2020 26(5):279-282 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Nahla Azzam Nora Alotaibi Majid Almadi Abdulrahman Aljebreen Source Type: research

Abnormal liver-related biomarkers in COVID-19 patients and the role of prealbumin
Conclusions: Abnormalities in albumin and prealbumin levels are common among COVID-19 patients and hypoprealbuminemia independently predicts adverse outcome and should be carefully considered in clinical practice. Moreover, changes in liver-related biomarkers is not a salient feature of COVID-19. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Tao Li Ying Guo Xianghua Zhuang Laigang Huang Xingqian Zhang Fengtao Wei Baohua Yang Source Type: research

A cross-sectional survey on the psychological impact of the COVID-19 pandemic on inflammatory bowel disease patients in Saudi Arabia
Conclusions: Many patients expressed symptoms of anxiety, although not depression. Female patients, patients educated till a high school diploma, and those with indeterminate colitis were more likely to have anxiety. IBD patients require greater attention during a pandemic to avoid adverse disease-related outcomes. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Mahmoud Mosli Mansour Alourfi Amani Alamoudi Almoutaz Hashim Omar Saadah Eman Al Sulais Turki AlAmeel Othman Alharbi Shakir Bakari Yaser Meeralam Seigha Alshobai Majid Alsahafi Hani Jawa Yousif Qari Source Type: research

Disability and quality of life before and during the COVID-19 outbreak: A cross-sectional study in inflammatory bowel disease patients
Conclusion: The current study showed that disability and HRQoL appears to be unaffected by the COVID-19 pandemic among our cohort, however further studies with longer follow up and larger sample size is needed. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Nahla A Azzam Abdulrahman Aljebreen Arwa Almuhareb Majid A Almadi Source Type: research

The psychological impact of COVID-19 pandemic on physicians in Saudi Arabia: A cross-sectional study
Conclusions: The COVID-19 pandemic had a negative psychological effect on physicians in Saudi Arabia. Gender, age, and previous exposure to similar traumatic events were predictive of psychological reactions to the pandemic in this population. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Eman Al Sulais Mahmoud Mosli Turki AlAmeel Source Type: research

COVID-19 and endoscopy services in intermediately affected countries: a position statement from the saudi gastroenterology association
Majid A Almadi, Abdulrahman M Aljebreen, Nahla Azzam, Nuha Alammar, Emad S Aljahdli, Fahad I Alsohaibani, Resheed Alkhiari, Abdulaziz O Almasoud, Mohammad S Al Beshir, Suliman Alshankiti, Ahmad W Alharbi, Mohammed Alkhathami, Faisal BatwaSaudi Journal of Gastroenterology 2020 26(5):240-248 With the global pandemic due to coronavirus disease 2019 (COVID-19), there has been a significant strain on healthcare facilities. The infectivity rate, as well as the rate of healthcare workers who have fallen ill to the disease, has raised concerns globally on the proper management of patients as well as the role of safe healthcare pr...
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Majid A Almadi Abdulrahman M Aljebreen Nahla Azzam Nuha Alammar Emad S Aljahdli Fahad I Alsohaibani Resheed Alkhiari Abdulaziz O Almasoud Mohammad S Al Beshir Suliman Alshankiti Ahmad W Alharbi Mohammed Alkhathami Faisal Batwa Source Type: research

Saudi association for the study of liver diseases and transplantation position statement on liver transplantation during the COVID-19 pandemic
Bandar Al-Judaibi, Reem Almaghrabi, Mohammed Alghamdi, Waleed K Al-Hamoudi, Mohammed AlQahtani, Faisal Abaalkhail, Mohammed Shagrani, Faisal M SanaiSaudi Journal of Gastroenterology 2020 26(5):233-239 The World Health Organization (WHO), on March 11th 2020, upgraded the status of the novel coronavirus disease (COVID-19) from epidemic to pandemic. Over two million individuals have been infected with SARS-CoV-2, the virus causing COVID-19, and as of April, 14th 2020, there were over 5000 confirmed cases in Saudi Arabia (SA). Many countries, including SA, have imposed major restrictions on travel, and everyday life, and the ...
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Bandar Al-Judaibi Reem Almaghrabi Mohammed Alghamdi Waleed K Al-Hamoudi Mohammed AlQahtani Faisal Abaalkhail Mohammed Shagrani Faisal M Sanai Source Type: research

Gastrointestinal and liver manifestations of COVID-19
Janice Cheong, Nichoals Bartell, Thoetchai Peeraphatdit, Mahmoud Mosli, Bandar Al-JudaibiSaudi Journal of Gastroenterology 2020 26(5):226-232 The novel coronavirus 2 (SARS-CoV-2) has spread worldwide. While patients typically present with fever and symptoms of a respiratory illness, patients have also presented with gastrointestinal symptoms such as diarrhea, vomiting and abdominal pain. In addition, some patients were reported to have liver injury. In this article, we review gastrointestinal and liver aspects of COVID-19. In addition, we provide general gastroenterologists with guidance on the management of patients with...
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Janice Cheong Nichoals Bartell Thoetchai Peeraphatdit Mahmoud Mosli Bandar Al-Judaibi Source Type: research

COVID-19 in gastroenterology and hepatology: Living with the realities of a historic 21st century pandemic
Eric M Yoshida, Trana Hussaini, Majid AlsahafiSaudi Journal of Gastroenterology 2020 26(5):223-225 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 17, 2020 Category: Gastroenterology Authors: Eric M Yoshida Trana Hussaini Majid Alsahafi Source Type: research

LncRNA NEAT1 modulates sorafenib resistance in hepatocellular carcinoma through regulating the miR-149-5p/AKT1 axis
Conclusions: NEAT1/miR-149-5p/AKT1 pathway-based therapy might be a potential clinical application for HCC patients. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 28, 2020 Category: Gastroenterology Authors: Yuexiang Niu Gongen Tang Xiuli Wu Chaoyu Wu Source Type: research

Utility of inflammatory markers to predict adverse outcome in acute pancreatitis: A retrospective study in a single academic center
Conclusion: Our data show persistently low LMR that is associated with severe AP and a value of <2.0 can be used clinically to predict severe AP on admission. It also shows that elevated NLR is associated with complicated AP and prolonged hospital stay with a value >10.5 that can be used to predict severe complicated AP and to monitor response to treatment over time. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 28, 2020 Category: Gastroenterology Authors: Mohamad Mubder Banreet Dhindsa Danny Nguyen Syed Saghir Chad Cross Ranjit Makar Gordon Ohning Source Type: research

Risk of neutropenia in inflammatory bowel disease patients treated with TNF inhibitors: A single-center, retrospective cohort study
Conclusions: In this study, mild neutropenia was common among patients with IBD on TNFi. Future prospective studies are required to further clarify the significance of neutropenia in patients with IBD receiving TNFi. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 28, 2020 Category: Gastroenterology Authors: Dimah AlAskar Mais AlSardi Eman Al Sulais Mahmoud Mosli Turki AlAmeel Source Type: research

Prevalence of biopsy-proven nonalcoholic fatty liver among patients with gallstone disease
Conclusions: The prevalence of NAFLD among GD patients is high. High BMI and diabetes are independent factors associated with NAFLD in GD patients. The results suggest that there may be a need for routine liver biopsy in selected patients during cholecystectomy. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 28, 2020 Category: Gastroenterology Authors: Faisal A Alsaif Sara H Alqahtani Amani M Alsadoon Khalid A Alswat Ayman A Abdo Mazen M Hassanain Abdulsalam B Alsharabi Ghadeer R Aljuhani Hisham M Alkhalidi Mohammad S Elsharkawy Maram A Alotaibi Faisal M Sanai Waleed K Al-hamoudi Source Type: research

LncRNA NEAT1 modulates sorafenib resistance in hepatocellular carcinoma through regulating the miR-149-5p/AKT1 axis
Conclusions: NEAT1/miR-149-5p/AKT1 pathway-based therapy might be a potential clinical application for HCC patients. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 28, 2020 Category: Gastroenterology Authors: Yuexiang Niu Gongen Tang Xiuli Wu Chaoyu Wu Source Type: research

Biliary anatomy and pancreatic duct variations: A cross-sectional study
Conclusion: Variations in biliary anatomy and pancreatic duct are very diverse and extend from the intrahepatic biliary system down to the pancreas. Performing a similar study on a larger population is mandatory to illustrate the range of variations present within the community. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 28, 2020 Category: Gastroenterology Authors: Murad Aljiffry Mohammad Abbas Mohammad A. M. Wazzan Ahmed H Abduljabbar Safiyah Aloufi Emad Aljahdli Source Type: research

Development and validation of metric-based-training to proficiency simulation curriculum for upper gastrointestinal endoscopy using a novel assessment checklist
Conclusion: The Fundamentals of Gastrointestinal Endoscopy simulation training curriculum and its SESAS global assessment tool have been primarily validated and can serve as a valuable addition to the gastroenterology fellowship programs. Follow up study of trainee performance in workplaces is recommended for consequences validation. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 28, 2020 Category: Gastroenterology Authors: Nahla Azzam Nehal Khamis Majid Almadi Faisal Batwa Fahad Alsohaibani Abdulrahman Aljebreen Ahmad Alharbi Yasser Alaska Turki Alameel Peter Irving Richard M Satava Source Type: research

The association between SNPs rs1800591 and rs3816873 of the MTTP gene and nonalcoholic fatty liver disease: A meta-analysis
Conclusion: The present meta-analysis revealed that the rs1800591 and rs3816873 polymorphisms of the MTTP gene are uncommon in NAFLD. However, the G allele of rs1800591 was more likely to be correlated to NASH susceptibility. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 28, 2020 Category: Gastroenterology Authors: Jie Tan Jian Zhang Zhenzhen Zhao Jie Zhang Mengzhen Dong Xuefeng Ma Shousheng Liu Yongning Xin Source Type: research

Training to competency: Are we ready for a radical reform ?
Hani LababidiSaudi Journal of Gastroenterology 2020 26(4):169-170 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 28, 2020 Category: Gastroenterology Authors: Hani Lababidi Source Type: research

Circulating tumor cells in whole process management of gastrointestinal stromal tumor in a real-life setting
Conclusions: In the current study, we assessed the CTCs and CTM of GIST patients in various disease progressions and identified clinicopathological factors influencing the detection of CTCs and CTM. These results are instructive for clinicians to understand CTCs/CTM in GIST patients. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - May 26, 2020 Category: Gastroenterology Authors: Qiang Zhang Kangjing Xu Ming Chen Yongchang Miao Nuofan Wang Zekuan Xu Hao Xu Source Type: research

Stachyose modulates gut microbiota and alleviates dextran sulfate sodium-induced acute colitis in mice
Conclusions: Our results suggested that stachyose increased beneficial microbiota and bacterial diversity to alleviate acute colitis in mice, which might be a new promising option to UC patients. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - May 26, 2020 Category: Gastroenterology Authors: Liwen He Feiran Zhang Zhengyang Jian Jiachen Sun Jiamin Chen Vuekhang Liapao Qing He Source Type: research