Chronic hepatitis B patients: A relation of age and comorbidities
Ashish K Vyas, Anirudh K SinghSaudi Journal of Gastroenterology 2019 25(2):141-141 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Ashish K Vyas Anirudh K Singh Source Type: research

Precision medicine in colorectal cancer
Mohammad Azhar AzizSaudi Journal of Gastroenterology 2019 25(2):139-140 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Mohammad Azhar Aziz Source Type: research

Predictors of failure of endoscopic retrograde cholangiography in clearing bile duct stone on the initial procedure
Conclusion: A few of the characteristics that are found on cholangiography at the index ERCP could be used to identify patients that might require more than one ERCP to clear the biliary system from stones. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Majid A Almadi Mohanned Eltayeb Salem Thaniah Faisal Alrashed Mohammad A Aljebreen Othman R Alharbi Nahla Azzam Abdulrahman M Aljebreen Source Type: research

Accuracy of invasive and noninvasive methods of Helicobacter pylori infection diagnosis in Saudi children
Conclusion: RUT is a valuable diagnostic method for identifying H. pylori with the highest sensitivity compared to AD and SAT. All diagnostic tests showed moderate-to-high specificities but BC and histology showed the highest specificity. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Mohammed Hasosah Source Type: research

Circular RNA ARHGAP26 is over-expressed and its downregulation inhibits cell proliferation and promotes cell apoptosis in gastric cancer cells
Conclusion: The circ-ARHGAP26 is over-expressed and its downregulation inhibits cell proliferation and promotes cells apoptosis in GC cells. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: LV Wangxia Yang Fang Yongjun Liu Yazhen Zhao Zhong Shi Haijun Zhong Source Type: research

Presence of pink-color sign within 1 min after iodine staining has high diagnostic accordance rate for esophageal high-grade intraepithelial neoplasia/invasive cancer
Conclusion: Appearance of the PCS within 1 min after iodine staining has a higher diagnostic accordance rate for esophageal HGIN/invasive cancer than appearance of the PCS at 2 min. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Jia-Yao Zheng Ya-Hua Chen Yang-Yang Chen Xiao-Ling Zheng Shi-Shun Zhong Wan-Yin Deng Jin-Hui Zheng Xian-Bin Guo Li-Ying Gao Wei Liang Source Type: research

Major bleeding risk of endoscopic sphincterotomy versus endoscopic papillary balloon dilatation in hemodialysis patients
Conclusion: Post-ERCP, post-EST, and post-EPBD major bleeding rates were all higher in HD patients in this study. EPBD resulted in lower postprocedure major bleeding events than EST in the non-HD population, but it failed to provide the reduction in bleeding events needed to perform endoscopic hemostasis in HD patients. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Ming-Chang Tsai Chi-Chih Wang Yao-Tung Wang Tzu-Wei Yang Hsuan-Yi Chen Ming-Hseng Tseng Chun-Che Lin Source Type: research

& #945;-Smooth muscle actin expression predicts the outcome of Kasai portoenterostomy in biliary atresia
Conclusion: α-SMA expression may be a potential predictor of jaundice clearance and native liver survival after KPE. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Priya Ramachandran Ashitha K Unny Mukul Vij Mohamed Safwan Muthukrishnan Saravana Balaji Mohamed Rela Source Type: research

Are patients aware of potential risks of weight reduction surgery ? An internet based survey
Conclusion: Two-thirds of the general population appears to be aware of the potential acute complications associated with bariatric surgery. Furthermore, awareness seems to be higher in females, individuals who had previously undergone weight reduction surgery, and health care workers. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Abdullah A Alamri Abdulrahman I Alsadiqi Abdulwahab Dahlawi Ahmad Alghamdi Majed Alnefaie Mohammed Alhazmi Omar Tewfik Adel Almaymuni Hatim Al-Abbadi Mahmoud Mosli Source Type: research

Use of image-enhanced endoscopy in the characterization of colorectal polyps: Still some ways to go
Conclusion: There remain areas of improvement in the performance of endoscopists in practice and would recommend more dedicated training programs, which could make use of asynchronous technological platforms. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Othman R Alharbi Nouf S Alballa Areej S AlRajeh Lulwah S Alturki Ibrahim M Alfuraih Mouhab R Jamalaldeen Majid A Almadi Source Type: research

Comparison of long-term efficacy between endoscopic and percutaneous biliary drainage for resectable extrahepatic cholangiocarcinoma with biliary obstruction: A systematic review and meta-analysis
Conclusion: The conclusion that EBD was superior to PTBD in OS for resectable extrahepatic cholangiocarcinoma with biliary obstruction is less convincing, and more trials need to be conducted in future. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Lei Wang Nanping Lin Fuli Xin Yongyi Zeng Jingfeng Liu Source Type: research

Hepatitis B care pathway in Saudi Arabia: Current situation, gaps and actions
Abdulrahman A Aljumah, Mohamed Babatin, Almoataz Hashim, Faisal Abaalkhail, Nathalie Bassil, Mohamed Safwat, Faisal M SanaiSaudi Journal of Gastroenterology 2019 25(2):73-80 Hepatitis B virus (HBV) infection remains a public health problem worldwide. In this review, we aim to assess the current situation of the HBV care pathway in the Kingdom of Saudi Arabia (KSA), identify gaps/barriers therein, and recommend initiatives to be taken to improve the management of such patients. Towards this end, a literature search was conducted in PubMed and free Internet searches. Interviews with individuals and focus group discussions w...
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Abdulrahman A Aljumah Mohamed Babatin Almoataz Hashim Faisal Abaalkhail Nathalie Bassil Mohamed Safwat Faisal M Sanai Source Type: research

Image enhanced endoscopy: Optical diagnosis or optical illusion ?
Gaius Loncroft-Wheaton, Pradeep BhandariSaudi Journal of Gastroenterology 2019 25(2):71-72 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Gaius Loncroft-Wheaton Pradeep Bhandari Source Type: research

In-hospital post-transplant acute hepatitis A viral (HAV) infection in a liver transplant recipient who was HAV seropositive pre-transplant
We report a case of acute hepatitis A infection in a liver transplant recipient. This individual had immunity to hepatitis A with protective IgG antibodies and presented with abnormal liver biochemistry in the post-transplant in-patient setting. Hepatitis A infection was confirmed by positive HAV IgM whereas other etiologies, including acute cellular rejection, were ruled out by laboratory tests and liver biopsies. He was treated conservatively with supportive care and liver enzymes recovered to normal baseline. Despite adequate pre-transplant immunity, in the post-transplant setting there may be loss of protective immunit...
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Julie Zhu Fatema Alalkim Trana Hussaini Siegfried R Erb Vladimir Marquez Mel Krajden Douglas Webber Eric M Yoshida Source Type: research

Low expression of MUC2 is associated with longer disease-free survival in patients with colorectal carcinoma
Conclusion: MUC2 immunostaining may have distinct clinical significance and provide valuable information and could be considered as an important independent prognostic factor while planning the adjuvant therapy in CRC. In future perspective, characterization of MUC2 immunostaining on a large number of cases and molecular studies may be needed. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Jaudah Al-Maghrabi Shabnum Sultana Wafaey Gomaa Source Type: research

Treatment efficacy of ledipasvir/sofosbuvir for 8 weeks in non-cirrhotic chronic hepatitis C genotype 4 patients
Conclusions: An 8-week regimen of LDV/SOF was well tolerated and efficacious in this treatment-naïve, non-cirrhotic HCV GT4–infected population. This study provides valuable information on a short treatment regimen for HCV GT4 infection in a real-world setting. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Mohammed A Babatin Abdullah S AlGhamdi Abdullah M Assiri Haziz AlBiladi Hammad S AlOthmani Mohammed H Mogharbel Wedad Mahallawi Tarik Asselah Faisal M Sanai Source Type: research

High HOXD4 protein expression in gastric adenocarcinoma tissues indicates unfavorable clinical outcomes
Conclusions: Our study demonstrated that overexpression of HOXD4 was significantly correlated with poorer prognosis of gastric adenocarcinoma patients, indicating the potential of HOXD4 as a novel clinical predictive biomarker and drug target. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Hui Liu Hequn Tian Jing Zhao Yong Jia Source Type: research

Association between hypokalemia and small bowel capsule endoscopy completion rates in patients in South China: A prospective single-center study
Conclusion: Hypokalemia may decrease the SBCE completion rate. Physicians should consider the possibility of hypokalemia after bowel preparation because this condition is not rare. Potassium deficiencies should be rectified prior to performing SBCE procedures to increase the SBCE completion rate. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Huo-Ye Gan Tie-Li Peng Kai-Hua Su Lin-Li Zhao Li-Qin Jian Rong-Jiao Yang Han-Xian Zhang Ru-Yin Pan Source Type: research

The gap between knowledge and undergoing colorectal cancer screening using the Health Belief Model: A national survey
Conclusion: Although the majority of participants were willing to undergo screening, no significant correlation between knowledge and willingness to undergo screening were predictors of screening uptake. Other areas that could be targeted in the promotion of CRC screening uptake to bridge the gap between “knowing” and “doing” should be explored. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Majid A Almadi Faisal Alghamdi Source Type: research

Findings during screening colonoscopies in a Middle Eastern cohort
Conclusion: The prevalence of polyps and adenomas in this cohort is less than that reported in the Western populations. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Majid A Almadi Abed Allehibi Mohammad A Aljebreen Othman R Alharbi Nahla Azzam Abdulrahman M Aljebreen Source Type: research

A meta-analysis of early oral refeeding and quickly increased diet for patients with mild acute pancreatitis
Conclusion: Pure EORF or QID caused no damage to patients with mild acute pancreatitis, and EORF could significantly decrease the LOHS. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Jiran Zhang Sha Zhu Dingyu Tan Aiwen Ma Yan Yang Jiyang Xu Source Type: research

Inflammation and pancreatic cancer: An updated review
Kamleshsingh Shadhu, Chunhua XiSaudi Journal of Gastroenterology 2019 25(1):3-13 Pancreatic cancer is a devastating disease with poor prognosis in the modern era. Inflammatory processes have emerged as key mediators of pancreatic cancer development and progression. Recently, studies have been carried out to investigate the underlying mechanisms that contribute to tumorigenesis induced by inflammation. In this review, the role of inflammation in the initiation and progression of pancreatic cancer is discussed. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Kamleshsingh Shadhu Chunhua Xi Source Type: research

Colorectal cancer screening in middle eastern countries: Current status and future strategies to enhance screening
Martin C. S. Wong, Francis K. L. ChanSaudi Journal of Gastroenterology 2019 25(1):1-2 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - January 28, 2019 Category: Gastroenterology Authors: Martin C. S. Wong Francis K. L. Chan Source Type: research

The characteristics of 83 giant peptic ulcers in Chinese children: Evaluation and follow-up
Conclusions: This study suggests that GPUs are strongly associated with H. pylori infection in Chinese children. Duodenal ulcers are the main type of GPU in patients older than 6 years. Appropriate diagnosis, treatment and follow-up are necessary for children with GPUs. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 19, 2018 Category: Gastroenterology Authors: Zifei Tang Jieru Shi Min Ji Peng Shi Zhiheng Huang Ying Huang Source Type: research

Initial experience of video capsule endoscopy at a tertiary center in Saudi Arabia
Conclusion: The diagnostic yield of VCE for Saudi patients with OGIB is comparable to that reported internationally; however, data for other VCE indications, including inflammatory bowel disease, are still lacking. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 19, 2018 Category: Gastroenterology Authors: Abdulrahman Alkhormi Mohammed Y Memon Ahmad Elhafi Mishal Aljohani Abdullah Aljahdali Adil Khatimi Amer Rizvi Khaled Shaban Ghulam Yazdani Mohammed Alnasser Source Type: research

The efficacy of temporary placement of nasobiliary drainage following endoscopic metal stenting to prevent post-ERCP cholangitis in patients with cholangiocarcinoma
Conclusions: The temporary placement of ENBD following EMBE is a simple and effective treatment modality to prevent post-ERCP cholangitis, especially in patients with hilar cholangiocarcinoma. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 19, 2018 Category: Gastroenterology Authors: Xinjian Wan Sumin Chen Qiuyan Zhao Tian Li Shengzheng Luo Xiaobo Cai Yingchun Ren Lanting Yu Baiwen Li Source Type: research

Bone mineral density loss in patients with cirrhosis
Conclusions: The study showed that cirrhotic patients are at increased susceptibility of having decreased BMD, particularly at the LS and it highlights the need for preventive measures, especially for female patients. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 19, 2018 Category: Gastroenterology Authors: Ibrahim N Muhsen Omar AlFreihi Faisal Abaalkhail Abdullah AlKhenizan Mohammed Khan Abdelmoneim Eldali Fahad Alsohaibani Source Type: research

Biologic agents in inflammatory bowel disease & #8211; quality of internet website information
Conclusions: The combined quality of Internet web-based resources used for each drug was fairly consistent in scoring (intermediate to slightly above average). There was no significant advantage in the overall combined scores of the pooled physician-recommended websites when compared with the patient-searched websites. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 19, 2018 Category: Gastroenterology Authors: Rymon Rofaiel Nilesh Chande Source Type: research

Real-world single-center experience with entecavir and tenofovir disoproxil fumarate in treatment-na & #239;ve and experienced patients with chronic hepatitis B
Conclusion: Both ETV and TDF therapy resulted in a high CVR, and the annual incidence rates of HCC and other cirrhosis-related complications were not significantly different between the two treatment groups. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 19, 2018 Category: Gastroenterology Authors: Young Min Kim Hyun Phil Shin Joung Il Lee Kwang Ro Joo Jae Myung Cha Jung Won Jeon Jin Young Yoon Min Seob Kwak Source Type: research

Radiofrequency ablation versus surgical resection in elderly patients with early-stage hepatocellular carcinoma in the era of organ shortage
Conclusion: Treatment strategies for elderly patients (≥65 years) with single HCC ≤5 cm should emphasize SR as the primary therapy, while RFA can be an alternative to SR for those>75 years with single HCC ≤3 cm. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 19, 2018 Category: Gastroenterology Authors: Bin Yu Youming Ding Xiaofeng Liao Changhua Wang Bin Wang Xiaoyan Chen Source Type: research

Water exchange versus air insufflation for colonoscopy: A meta-analysis
Conclusion: This meta-analysis confirmed that WE method could significantly increase ADR/PDR and improve patients' acceptance of colonoscopy, while reducing the degree of pain and minimize the need for on-demand sedation and adjunct maneuvers, despite requiring more cecal intubation time. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 19, 2018 Category: Gastroenterology Authors: Yang Liu Qing-Ke Huang Xiu-Li Dong Piao-Piao Jin Source Type: research

Surgical resection vs radiofrequency ablation in older adults with early stage hepatocellular carcinoma: Where do we stand ?
Bandar Al-Judaibi, M Katherine DokusSaudi Journal of Gastroenterology 2018 24(6):309-310 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - November 19, 2018 Category: Gastroenterology Authors: Bandar Al-Judaibi M Katherine Dokus Source Type: research

Extraintestinal manifestations of pediatric inflammatory bowel disease in Saudi Arabia
Mahmood D Al-MendalawiSaudi Journal of Gastroenterology 2018 24(5):307-307 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 10, 2018 Category: Gastroenterology Authors: Mahmood D Al-Mendalawi Source Type: research

Correlated non-nuclear COX2 and low HER2 expression confers a good prognosis in colorectal cancer
Conclusion: The study suggests that nuclear COX2 in combination with HER2 can serve as potential biomarkers for the clinical diagnosis and prognosis of CRC, and targeted inhibition of COX2 and HER2 might be an alternative strategy for the management of CRC. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 10, 2018 Category: Gastroenterology Authors: Fei-fei Zhou Rong Huang Jun Jiang Xiao-hong Zeng Shu-qian Zou Source Type: research

The role of the PLR & #8211;NLR combination in the prediction of the presence of Helicobacter pylori and its associated complications
Conclusion: We found the PLR–NLR combination to be a good predictor of HP presence and gastrointestinal complications associated with HP. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 10, 2018 Category: Gastroenterology Authors: Mustafa Kaplan Ihsan Ates Mahmut Yuksel Mehmet F Arikan Gulden Aydog Nesrin Turhan Volkan G & #246;kbulut Ertugrul Kayacetin Source Type: research

Gastric adenocarcinoma expressing human epidermal growth factor receptor in South Asian population
Conclusion: Her-2/neu is over-expressed in a limited group of gastric cancer patients in our population and indicates a significant strong association with low grades of gastric cancer. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 10, 2018 Category: Gastroenterology Authors: Asma Shabbir Muhammad Asif Qureshi Abdullah Bin Khalid Talat Mirza Asma Shaikh Syed Mehmood Hasan Source Type: research

Predictors of morbidity and mortality post emergency abdominal surgery: A national study
Conclusion: American Society of Anesthesiologist score, diagnosis, stoma formation and anastomotic leak are associated with 30-day mortality after emergency surgery in Saudi Arabia. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 10, 2018 Category: Gastroenterology Authors: Afnan Altamimi Mazen Hassanain Thamer Nouh Khawlah Ateeq Murad Aljiffry Abrar Nawawi Ghaith Al Saied Mohammed Riaz Huda Alanbar Abdullah Altamimi Saeed Alsareii Mashael Al-Mousa Abeer Al-shammari Saleh Alnuqaydan Amal Ghzwany Source Type: research

Mirizzi & #39;s syndrome: A scoring system for preoperative diagnosis
Conclusion: We propose a simple scoring system based on clinical, biochemical, and imaging parameters that can be useful for predicting MS in patients with complicated cholecystitis. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 10, 2018 Category: Gastroenterology Authors: Rachana D Tataria Hrishikesh P Salgaonkar Gaurav Maheshwari Premashish J Halder Source Type: research

Genetic susceptibility for celiac disease is highly prevalent in the Saudi population
Conclusion: We report one of the highest frequencies of CD-predisposing HLA-DQ genotypes among healthy general populations (52.7%) worldwide, which might partly explain the high prevalence of CD in the Saudi community. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 10, 2018 Category: Gastroenterology Authors: Abdulrahman Al-Hussaini Hanan Alharthi Awad Osman Nezar Eltayeb-Elsheikh Aziz Chentoufi Source Type: research

Is water exchange superior to water immersion for colonoscopy ? A systematic review and meta-analysis
Conclusions: This meta-analysis supports the hypothesis that WE is superior to WI in improving ADR, attenuating insertion pain and providing better bowel cleansing, but inferior in time and consumption of infused water consumption during insertion. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 10, 2018 Category: Gastroenterology Authors: Zhihao Chen Zhengqi Li Xinying Yu Guiqi Wang Source Type: research

The puzzling relationship between human leukocyte antigen HLA genes and celiac disease
Carlo Catassi, Giulia Naspi CatassiSaudi Journal of Gastroenterology 2018 24(5):257-258 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - September 10, 2018 Category: Gastroenterology Authors: Carlo Catassi Giulia Naspi Catassi Source Type: research

Erratum: Nonalcoholic fatty liver disease burden & #8211; Saudi Arabia and United Arab Emirates, 2017 & #8211;2030
Saudi Journal of Gastroenterology 2018 24(4):255-255 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 27, 2018 Category: Gastroenterology Source Type: research

The effect of virulence genotypes of Helicobacter pylori on eradication therapy in children
Conclusions: The cagA, vacA, and iceA genotypes of H. pylori are not associated with the efficacy of omeprazole-based triple therapy on the eradication of H. pylori infection in children. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 27, 2018 Category: Gastroenterology Authors: Shuang-Hong Zhang Xuan Zhu Bi-Min Li Hong Li Source Type: research

Expression and significance of interleukin-17 and interleukin-22 in the serum and the lower esophageal sphincter of patients with achalasia
Conclusion: Interleukin-17 and interleukin-22 are upregulated in the serum and LES in patients with AC, suggesting that both interleukin-17 and interleukin-22 are involved in the pathogenesis of AC, and that AC may be an immune-mediated inflammatory disease. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 27, 2018 Category: Gastroenterology Authors: Zeyu Wang Jun Zhang Jianwei Mi Huihui Ma Dongqiang Zhao Source Type: research

Prevalence and clinical predictors of LPR among patients diagnosed with GERD according to the reflux symptom index questionnaire
Conclusions: Contradictory to what is frequently reported, LPR commonly occurs and positively correlates with GERD. Several modifiable clinical predictors of LPR might exist, which highlight the importance of performing a complete clinical assessment of the patients with reflux symptoms. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 27, 2018 Category: Gastroenterology Authors: Mahmoud Mosli Bashaer Alkhathlan Abdulmalik Abumohssin Mazin Merdad Ameen Alherabi Osama Marglani Hani Jawa Talal Alkhatib Hani Z Marzouki Source Type: research

Evaluation of a modified rat model for functional dyspepsia
Conclusions: The modified rat model meets the diagnostic criteria of FD and can be used as a method for studying FD in animals. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 27, 2018 Category: Gastroenterology Authors: Qiankun Liang Yuan Yan Lanfang Mao Xiaojuan Du Jingjing Liang Junhong Liu Longde Wang Hongfang Li Source Type: research

Association of coagulopathy with the risk of bleeding after invasive procedures in liver cirrhosis
Conclusion: Severe thrombocytopenia significantly increased the risk of major bleeding after invasive procedures in cirrhosis. INR ≥ 1.5 significantly increased in-hospital mortality. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 27, 2018 Category: Gastroenterology Authors: Jing Li Bing Han Hongyu Li Han Deng Nahum M & #233;ndez-S & #225;nchez Xiaozhong Guo Xingshun Qi Source Type: research

Nonalcoholic fatty liver disease burden & #8211; Saudi Arabia and United Arab Emirates, 2017 & #8211;2030
Conclusions: Continued high rates of adult obesity and DM, in combination with aging populations, suggest that advanced liver disease and mortality attributable to NAFLD/NASH will increase across both countries. Reducing the growth of the NAFLD population, along with potential therapeutic options, will be needed to reduce liver disease burden. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 27, 2018 Category: Gastroenterology Authors: Khalid Alswat Abdulrahman A Aljumah Faisal M Sanai Faisal Abaalkhail Mohamed Alghamdi Waleed K Al Hamoudi Abdullah Al Khathlan Huda Al Quraishi Ahmed Al Rifai Mohamed Al Zaabi Mohamed A Babatin Chris Estes Almoutaz Hashim Homie Razavi Source Type: research

Protective association of TNFSF15 polymorphisms with Crohn & #39;s disease and ulcerative colitis: A meta-analysis
Conclusions: This meta-analysis suggests that TNFSF15 polymorphisms may contribute to genetic susceptibility of IBD. (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 27, 2018 Category: Gastroenterology Authors: Liwen He Jiamin Chen Jiachen Sun Junsheng Peng Qing He Source Type: research

Nonalcoholic fatty liver disease: One more reason to strengthen public health
Tareef AlaamaSaudi Journal of Gastroenterology 2018 24(4):199-200 (Source: The Saudi Journal of Gastroenterology)
Source: The Saudi Journal of Gastroenterology - July 27, 2018 Category: Gastroenterology Authors: Tareef Alaama Source Type: research