Sex- and Gender-Related Aspects in Pulmonary Hypertension

Biological sex and sociocultural gender are emerging as pivotal modifiers of health and diseases. Sex-based differences exist in the development, pathogenesis, and management of individuals with pulmonary arterial hypertension (PAH). The interplay between gender domains (ie, identity, roles, relations, and institutionalized gender) and PAH has been barely investigated. The aim of this narrative review is to describe up-to-date evidence on the integration of sex and gender in PAH research, highlighting areas for future investigation.

Source: Heart Failure Clinics - November 24, 2022 Category: Cardiology Authors: Anna D ’Agostino, Paola Guindani, Gerarda Scaglione, Alessandra Di Vincenzo, Sara Tamascelli, Riccardo Spaggiari, Andrea Salzano, Andrea D’Amuri, Alberto Maria Marra, Louise Pilote, Valeria Raparelli Source Type: research