Multi-target regulation of pro-inflammatory cytokine production by transcription factor Blimp-1

ConclusionBlimp-1 represses the production of multiple pro-inflammatory cytokines by directly binding the genomic region and restricting the nuclear translocation and transcriptional activity of NF- κB. This finding may provide potential therapeutic strategies for the cytokine storm-related diseases.
Source: Inflammation Research - Category: Research Source Type: research