Sub-chronic restraint stress suppresses sexual potency and erection efficiency by targeting the hypothalamic-pituitary-testicular axis and the NO/cGMP/PDE5 α pathway in adult rats.

Conclusion: The current findings suggest that psychological stressors, su ch as restraint stress, cause erectile dysfunction in adult male rats by modulating the hypothalamic-pituitary-testicular axis, oxidative balance, penile fibrosis, and the NO/cGMP/PDE5α pathway of penile erection.
Source: Neuroendocrinology - Category: Endocrinology Source Type: research