Clinical and Polysomnographic Characteristics of Nonobese and Obese Chinese Patients With Obstructive Sleep Apnea

Purpose: Obesity is a risk factor associated with the onset and exacerbation of obstructive sleep apnea (OSA). However, the majority of OSA patients in Asian populations are nonobese. To date, there have been insufficient large-scale studies of the differences in the clinical and polysomnographic features of obese and nonobese OSA patients in this population, and few studies have sought to identify predictors of OSA severity in affected obese and nonobese patients. Methods: We conducted a case-matched retrospective study, including 652 consecutive Chinese OSA patients (326 nonobese and 326 obese) to assess differences in demographic, clinical, and polysomnographic data between these two groups. Independent predictors of OSA severity were identified through multivariate linear regression analysis. Results: The age and gender distributions of our obese and nonobese OSA patient cohorts did not differ significantly (P> 0.05), and rates of comorbidities were comparable in these two patient groups (P> 0.05). Nonobese patients were more likely to report atypical symptoms of OSA, including insomnia (P
Source: Journal of Clinical Neurophysiology - Category: Neurology Tags: Original Research Source Type: research