A Case of Thrombotic Microangiopathy and Acute Sarcoidosis

We describe the case of a patient presenting with hypercalcemia, pancreatitis, and acute renal failure, followed by microangiopathic hemolytic anemia. Although there were no significant respiratory symptoms, thoracic radiology and mediastinal lymph node biopsy results were in keeping with sarcoidosis as the underlying cause of this multisystem presentation. Corticosteroids were commenced with clinical and biochemical improvement. This novel case highlights the need to consider sarcoidosis as part of the differential diagnosis for unusual multiorgan presentations and for early multidisciplinary involvement in such cases to permit optimal treatment.PMID:36344132 | DOI:10.1016/j.chest.2022.06.023

Source: Chest - November 7, 2022 Category: Respiratory Medicine Authors: Anthony W Martinelli William Dunn Mark E McClure Ieuan Walker Andrew Stewart Sumit Karia Stephen D Preston Sathia Thiru Nicholas Torpey Sanjay Ojha Emily Symington James A Nathan Source Type: research