Resistin impairs mitochondrial homeostasis via cyclase-associated protein 1-mediated fission, leading to obesity-induced metabolic diseases

One of the suggested mechanisms of obesity-induced insulin resistance is mitochondrial dysfunction in target tissues such as skeletal muscle. In our study, we examined whether resistin, an adipokine associated with obesity-mediated insulin resistance, induced metabolic disorders by impairing mitochondrial homeostasis.

Source: Metabolism - Clinical and Experimental - November 7, 2022 Category: Biomedical Science Authors: Han-Mo Yang, Joonoh Kim, Dasom Shin, Ju-Young Kim, Jihye You, Hyun-Chae Lee, Hyun-Duk Jang, Hyo-Soo Kim Source Type: research