White matter microstructure and sleep-wake disturbances in individuals at ultra-high risk of psychosis

ConclusionCompromised callosal microstructure in UHR individuals was related to objectively observed disruptions in sleep-wake functioning. Lower FA in ventrally located regions was associated with subjectively measured sleep-wake disturbances and was partly explained by psychopathology. These findings call for further investigation of sleep disturbances as a potential treatment target.
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research