Asiaticoside Prevents Oxidative Stress and Apoptosis in Endothelial Cells by Activating ROS-dependent p53/Bcl-2/Caspase-3 Signaling Pathway

CONCLUSION: AC alleviates t-BHP-induced oxidative injury and apoptosis in HUVECs through the ROS-dependent p53/Bcl-2/Caspase-3 signaling pathway. It may be a potential antioxidant applied in metabolic disorders and pharmaceutical products.PMID:36284389 | DOI:10.2174/1566524023666221024120825

Source: Molecular Medicine - October 26, 2022 Category: Molecular Biology Authors: Zhenwen Liang Yu Chen Rifang Gu Qi Guo Xuqiang Nie Source Type: research